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On a generalized false discovery rate

Abstract

The concept of kk-FWER has received much attention lately as an appropriate error rate for multiple testing when one seeks to control at least kk false rejections, for some fixed k1k\ge 1. A less conservative notion, the kk-FDR, has been introduced very recently by Sarkar [Ann. Statist. 34 (2006) 394--415], generalizing the false discovery rate of Benjamini and Hochberg [J. Roy. Statist. Soc. Ser. B 57 (1995) 289--300]. In this article, we bring newer insight to the kk-FDR considering a mixture model involving independent pp-values before motivating the developments of some new procedures that control it. We prove the kk-FDR control of the proposed methods under a slightly weaker condition than in the mixture model. We provide numerical evidence of the proposed methods' superior power performance over some kk-FWER and kk-FDR methods. Finally, we apply our methods to a real data set.

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