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Variational Latent Gaussian Process for Recovering Single-Trial Dynamics from Population Spike Trains

11 April 2016
Yuan Zhao
Il-Su Park
ArXiv (abs)PDFHTML
Abstract

A small number of common factors often explain most of the interdependence among simultaneously recorded neurons, a signature of underlying low-dimensional dynamics. We posit that simple neural coding and computation manifest as low-dimensional nonlinear dynamics implemented redundantly within a large population of neurons. Recovering the latent dynamics from observations can offer a deeper understanding of neural computation. We improve upon previously-proposed methods for recovering latent dynamics, which assume either an inappropriate observation model or linear dynamics. We propose a practical and efficient inference method for a generative model with explicit point process observations and an assumption of smooth nonlinear dynamics. We validate our method on both simulated data and population recording from primary visual cortex.

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