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Efficient computational algorithms for approximate optimal designs

Abstract

In this paper, we propose two simple yet efficient computational algorithms to obtain approximate optimal designs for multi-dimensional linear regression on a large variety of design spaces. We focus on the two commonly used optimal criteria, DD- and AA-optimal criteria. For DD-optimality, we provide an alternative proof for the monotonic convergence for DD-optimal criterion and propose an efficient computational algorithm to obtain the approximate DD-optimal design. We further show that the proposed algorithm converges to the DD-optimal design, and then prove that the approximate DD-optimal design converges to the continuous DD-optimal design under certain conditions. For AA-optimality, we provide an efficient algorithm to obtain approximate AA-optimal design and conjecture the monotonicity of the proposed algorithm. Numerical comparisons suggest that the proposed algorithms perform well and they are comparable or superior to some existing algorithms.

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