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An instrumental variable approach under dependent censoring

Test (Madrid) (TM), 2022
Abstract

This paper considers the problem of inferring the causal effect of a variable ZZ on a dependently censored survival time TT. We allow for unobserved confounding variables, such that the error term of the regression model for TT is correlated with the confounded variable ZZ. Moreover, TT is subject to dependent censoring. This means that TT is right censored by a censoring time CC, which is dependent on TT (even after conditioning out the effects of the measured covariates). A control function approach, relying on an instrumental variable, is leveraged to tackle the confounding issue. Further, it is assumed that TT and CC follow a joint regression model with bivariate Gaussian error terms and an unspecified covariance matrix such that the dependent censoring can be handled in a flexible manner. Conditions under which the model is identifiable are given, a two-step estimation procedure is proposed, and it is shown that the resulting estimator is consistent and asymptotically normal. Simulations are used to confirm the validity and finite-sample performance of the estimation procedure. Finally, the proposed method is used to estimate the causal effect of job training programs on unemployment duration.

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