The visual modeling method supports flexible interactions with rich graphical depictions of data, enabling users to explore the complexities of epidemiological analysis. However, most epidemiology visualizations do not support the combined analysis of objective factors that might influence the transmission situation, resulting in a dearth of quantitative and qualitative evidence. To address this issue, we have developed a portrait-based visual modeling method called +msRNAer. This method takes into account the spatiotemporal features of virus transmission patterns and multidimensional features of objective risk factors in communities, enabling portrait-based exploration and comparison in epidemiological analysis. We applied +msRNAer to aggregate COVID-19-related datasets in New South Wales, Australia, combining COVID-19 case numbers, geo-information, intervention events, and expert-supervised risk factors extracted from LGA-based censuses. We demonstrated the +msRNAer workflow and evaluated the feasibility, effectiveness, and usefulness by applying aggregated COVID-19-related datasets via one user study and three subject-driven case studies. According to positive feedback from experts, +msRNAer provides a general understanding of analyzing comprehension that not only compares relationships between cases in time-varying and risk factors through portraits but also supports navigation in fundamental geographical, timeline, and other factor comparisons. By adopting interactions, experts discovered functional and practical implications for potential patterns of long-standing community factors against the vulnerability faced by the pandemic. Experts confirm that +msRNAer is expected to deliver visual modeling benefits with spatiotemporal and multidimensional features in other epidemiological analysis scenarios.
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