An Ordinal Regression Framework for a Deep Learning Based Severity Assessment for Chest Radiographs
Patrick Wienholt
Alexander Hermans
Firas Khader
B. Puladi
Bastian Leibe
Christiane Kuhl
S. Nebelung
Daniel Truhn

Abstract
This study investigates the application of ordinal regression methods for categorizing disease severity in chest radiographs. We propose a framework that divides the ordinal regression problem into three parts: a model, a target function, and a classification function. Different encoding methods, including one-hot, Gaussian, progress-bar, and our soft-progress-bar, are applied using ResNet50 and ViT-B-16 deep learning models. We show that the choice of encoding has a strong impact on performance and that the best encoding depends on the chosen weighting of Cohen's kappa and also on the model architecture used. We make our code publicly available on GitHub.
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