BraTS-PEDs: Results of the Multi-Consortium International Pediatric Brain Tumor Segmentation Challenge 2023
Pediatric central nervous system tumors are the leading cause of cancer-related deaths in children. The five-year survival rate for high-grade glioma in children is less than 20%. The development of new treatments is dependent upon multi-institutional collaborative clinical trials requiring reproducible and accurate centralized response assessment. We present the results of the BraTS-PEDs 2023 challenge, the first Brain Tumor Segmentation (BraTS) challenge focused on pediatric brain tumors. This challenge utilized data acquired from multiple international consortia dedicated to pediatric neuro-oncology and clinical trials. BraTS-PEDs 2023 aimed to evaluate volumetric segmentation algorithms for pediatric brain gliomas from magnetic resonance imaging using standardized quantitative performance evaluation metrics employed across the BraTS 2023 challenges. The top-performing AI approaches for pediatric tumor analysis included ensembles of nnU-Net and Swin UNETR, Auto3DSeg, or nnU-Net with a self-supervised framework. The BraTSPEDs 2023 challenge fostered collaboration between clinicians (neuro-oncologists, neuroradiologists) and AI/imaging scientists, promoting faster data sharing and the development of automated volumetric analysis techniques. These advancements could significantly benefit clinical trials and improve the care of children with brain tumors.
View on arXiv@article{kazerooni2025_2407.08855,
title={ BraTS-PEDs: Results of the Multi-Consortium International Pediatric Brain Tumor Segmentation Challenge 2023 },
author={ Anahita Fathi Kazerooni and Nastaran Khalili and Xinyang Liu and Debanjan Haldar and Zhifan Jiang and Anna Zapaishchykova and Julija Pavaine and Lubdha M. Shah and Blaise V. Jones and Nakul Sheth and Sanjay P. Prabhu and Aaron S. McAllister and Wenxin Tu and Khanak K. Nandolia and Andres F. Rodriguez and Ibraheem Salman Shaikh and Mariana Sanchez Montano and Hollie Anne Lai and Maruf Adewole and Jake Albrecht and Udunna Anazodo and Hannah Anderson and Syed Muhammed Anwar and Alejandro Aristizabal and Sina Bagheri and Ujjwal Baid and Timothy Bergquist and Austin J. Borja and Evan Calabrese and Verena Chung and Gian-Marco Conte and James Eddy and Ivan Ezhov and Ariana M. Familiar and Keyvan Farahani and Deep Gandhi and Anurag Gottipati and Shuvanjan Haldar and Juan Eugenio Iglesias and Anastasia Janas and Elaine Elaine and Alexandros Karargyris and Hasan Kassem and Neda Khalili and Florian Kofler and Dominic LaBella and Koen Van Leemput and Hongwei B. Li and Nazanin Maleki and Zeke Meier and Bjoern Menze and Ahmed W. Moawad and Sarthak Pati and Marie Piraud and Tina Poussaint and Zachary J. Reitman and Jeffrey D. Rudie and Rachit Saluja and MIcah Sheller and Russell Takeshi Shinohara and Karthik Viswanathan and Chunhao Wang and Benedikt Wiestler and Walter F. Wiggins and Christos Davatzikos and Phillip B. Storm and Miriam Bornhorst and Roger Packer and Trent Hummel and Peter de Blank and Lindsey Hoffman and Mariam Aboian and Ali Nabavizadeh and Jeffrey B. Ware and Benjamin H. Kann and Brian Rood and Adam Resnick and Spyridon Bakas and Arastoo Vossough and Marius George Linguraru },
journal={arXiv preprint arXiv:2407.08855},
year={ 2025 }
}