CardioSyntax: end-to-end SYNTAX score prediction -- dataset, benchmark and method

The SYNTAX score has become a widely used measure of coronary disease severity, crucial in selecting the optimal mode of the revascularization procedure. This paper introduces a new medical regression and classification problem - automatically estimating SYNTAX score from coronary angiography. Our study presents a comprehensive CardioSYNTAX dataset of 3,018 patients for the SYNTAX score estimation and coronary dominance classification. The dataset features a balanced distribution of individuals with zero and non-zero scores. This dataset includes a first-of-its-kind, complete coronary angiography samples captured through a multi-view X-ray video, allowing one to observe coronary arteries from multiple perspectives. Furthermore, we present a novel, fully automatic end-to-end method for estimating the SYNTAX. For such a difficult task, we have achieved a solid coefficient of determination R2 of 0.51 in score value prediction and 77.3% accuracy for zero score classification.

@article{ponomarchuk2025_2407.19894,
  title={ CardioSyntax: end-to-end SYNTAX score prediction -- dataset, benchmark and method },
  author={ Alexander Ponomarchuk and Ivan Kruzhilov and Galina Zubkova and Artem Shadrin and Ruslan Utegenov and Ivan Bessonov and Pavel Blinov },
  journal={arXiv preprint arXiv:2407.19894},
  year={ 2025 }
}