Precise Insulin Delivery for Artificial Pancreas: A Reinforcement Learning Optimized Adaptive Fuzzy Control Approach

This paper explores the application of reinforcement learning to optimize the parameters of a Type-1 Takagi-Sugeno fuzzy controller, designed to operate as an artificial pancreas for Type 1 diabetes. The primary challenge in diabetes management is the dynamic nature of blood glucose levels, which are influenced by several factors such as meal intake and timing. Traditional controllers often struggle to adapt to these changes, leading to suboptimal insulin administration. To address this issue, we employ a reinforcement learning agent tasked with adjusting 27 parameters of the Takagi-Sugeno fuzzy controller at each time step, ensuring real-time adaptability. The study's findings demonstrate that this approach significantly enhances the robustness of the controller against variations in meal size and timing, while also stabilizing glucose levels with minimal exogenous insulin. This adaptive method holds promise for improving the quality of life and health outcomes for individuals with Type 1 diabetes by providing a more responsive and precise management tool. Simulation results are given to highlight the effectiveness of the proposed approach.

@article{mameche2025_2503.06701,
  title={ Precise Insulin Delivery for Artificial Pancreas: A Reinforcement Learning Optimized Adaptive Fuzzy Control Approach },
  author={ Omar Mameche and Abdelhadi Abedou and Taqwa Mezaache and Mohamed Tadjine },
  journal={arXiv preprint arXiv:2503.06701},
  year={ 2025 }
}