Prompting Medical Vision-Language Models to Mitigate Diagnosis Bias by Generating Realistic Dermoscopic Images

Artificial Intelligence (AI) in skin disease diagnosis has improved significantly, but a major concern is that these models frequently show biased performance across subgroups, especially regarding sensitive attributes such as skin color. To address these issues, we propose a novel generative AI-based framework, namely, Dermatology Diffusion Transformer (DermDiT), which leverages text prompts generated via Vision Language Models and multimodal text-image learning to generate new dermoscopic images. We utilize large vision language models to generate accurate and proper prompts for each dermoscopic image which helps to generate synthetic images to improve the representation of underrepresented groups (patient, disease, etc.) in highly imbalanced datasets for clinical diagnoses. Our extensive experimentation showcases the large vision language models providing much more insightful representations, that enable DermDiT to generate high-quality images. Our code is available atthis https URL

@article{munia2025_2504.01838,
  title={ Prompting Medical Vision-Language Models to Mitigate Diagnosis Bias by Generating Realistic Dermoscopic Images },
  author={ Nusrat Munia and Abdullah-Al-Zubaer Imran },
  journal={arXiv preprint arXiv:2504.01838},
  year={ 2025 }
}