Explanation-Driven Interventions for Artificial Intelligence Model Customization: Empowering End-Users to Tailor Black-Box AI in Rhinocytology

The integration of Artificial Intelligence (AI) in modern society is transforming how individuals perform tasks. In high-risk domains, ensuring human control over AI systems remains a key design challenge. This article presents a novel End-User Development (EUD) approach for black-box AI models, enabling users to edit explanations and influence future predictions through targeted interventions. By combining explainability, user control, and model adaptability, the proposed method advances Human-Centered AI (HCAI), promoting a symbiotic relationship between humans and adaptive, user-tailored AI systems.