Diffusion Probabilistic Models (DPMs) have demonstrated significant potential in 3D medical image segmentation tasks. However, their high computational cost and inability to fully capture global 3D contextual information limit their practical applications. To address these challenges, we propose a novel text-guided diffusion model framework, TextDiffSeg. This method leverages a conditional diffusion framework that integrates 3D volumetric data with natural language descriptions, enabling cross-modal embedding and establishing a shared semantic space between visual and textual modalities. By enhancing the model's ability to recognize complex anatomical structures, TextDiffSeg incorporates innovative label embedding techniques and cross-modal attention mechanisms, effectively reducing computational complexity while preserving global 3D contextual integrity. Experimental results demonstrate that TextDiffSeg consistently outperforms existing methods in segmentation tasks involving kidney and pancreas tumors, as well as multi-organ segmentation scenarios. Ablation studies further validate the effectiveness of key components, highlighting the synergistic interaction between text fusion, image feature extractor, and label encoder. TextDiffSeg provides an efficient and accurate solution for 3D medical image segmentation, showcasing its broad applicability in clinical diagnosis and treatment planning.
View on arXiv@article{ma2025_2504.11825,
title={ TextDiffSeg: Text-guided Latent Diffusion Model for 3d Medical Images Segmentation },
author={ Kangbo Ma },
journal={arXiv preprint arXiv:2504.11825},
year={ 2025 }
}