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MA-COIR: Leveraging Semantic Search Index and Generative Models for Ontology-Driven Biomedical Concept Recognition

19 May 2025
Shanshan Liu
Noriki Nishida
Rumana Ferdous Munne
Narumi Tokunaga
Yuki Yamagata
Kouji Kozaki
Yuji Matsumoto
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Abstract

Recognizing biomedical concepts in the text is vital for ontology refinement, knowledge graph construction, and concept relationship discovery. However, traditional concept recognition methods, relying on explicit mention identification, often fail to capture complex concepts not explicitly stated in the text. To overcome this limitation, we introduce MA-COIR, a framework that reformulates concept recognition as an indexing-recognition task. By assigning semantic search indexes (ssIDs) to concepts, MA-COIR resolves ambiguities in ontology entries and enhances recognition efficiency. Using a pretrained BART-based model fine-tuned on small datasets, our approach reduces computational requirements to facilitate adoption by domain experts. Furthermore, we incorporate large language models (LLMs)-generated queries and synthetic data to improve recognition in low-resource settings. Experimental results on three scenarios (CDR, HPO, and HOIP) highlight the effectiveness of MA-COIR in recognizing both explicit and implicit concepts without the need for mention-level annotations during inference, advancing ontology-driven concept recognition in biomedical domain applications. Our code and constructed data are available atthis https URL.

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@article{liu2025_2505.12964,
  title={ MA-COIR: Leveraging Semantic Search Index and Generative Models for Ontology-Driven Biomedical Concept Recognition },
  author={ Shanshan Liu and Noriki Nishida and Rumana Ferdous Munne and Narumi Tokunaga and Yuki Yamagata and Kouji Kozaki and Yuji Matsumoto },
  journal={arXiv preprint arXiv:2505.12964},
  year={ 2025 }
}
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