Dual-Alignment Knowledge Retention for Continual Medical Image Segmentation

Continual learning in medical image segmentation involves sequential data acquisition across diverse domains (e.g., clinical sites), where task interference between past and current domains often leads to catastrophic forgetting. Existing continual learning methods fail to capture the complex dependencies between tasks. We introduce a novel framework that mitigates forgetting by establishing and enhancing complex dependencies between historical data and the network in the present task. Our framework features a dual-alignment strategy, the cross-network alignment (CNA) module aligns the features extracted from the bottleneck layers of the current and previous networks, respectively, while the cross-representation alignment (CRA) module aligns the features learned by the current network from historical buffered data and current input data, respectively. Implementing both types of alignment is a non-trivial task. To address this, we further analyze the linear and nonlinear forms of the well-established Hilbert-Schmidt Independence Criterion (HSIC) and deliberately design feature mapping and feature pairing blocks within the CRA module. Experiments on medical image segmentation task demonstrate our framework's effectiveness in mitigating catastrophic forgetting under domain shifts.