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Accelerating Scientific Research with Gemini: Case Studies and Common Techniques

David P. Woodruff
Vincent Cohen-Addad
Lalit Jain
Jieming Mao
Song Zuo
MohammadHossein Bateni
Simina Branzei
Michael P. Brenner
Lin Chen
Ying Feng
Lance Fortnow
Gang Fu
Ziyi Guan
Zahra Hadizadeh
Mohammad T. Hajiaghayi
Mahdi JafariRaviz
Adel Javanmard
Karthik C. S.
Ken-ichi Kawarabayashi
Ravi Kumar
Silvio Lattanzi
Euiwoong Lee
Yi Li
Ioannis Panageas
Dimitris Paparas
Benjamin Przybocki
Bernardo Subercaseaux
Ola Svensson
Shayan Taherijam
Xuan Wu
Eylon Yogev
Morteza Zadimoghaddam
Samson Zhou
Vahab Mirrokni
Main:128 Pages
24 Figures
3 Tables
Appendix:23 Pages
Abstract

Recent advances in large language models (LLMs) have opened new avenues for accelerating scientific research. While models are increasingly capable of assisting with routine tasks, their ability to contribute to novel, expert-level mathematical discovery is less understood. We present a collection of case studies demonstrating how researchers have successfully collaborated with advanced AI models, specifically Google's Gemini-based models (in particular Gemini Deep Think and its advanced variants), to solve open problems, refute conjectures, and generate new proofs across diverse areas in theoretical computer science, as well as other areas such as economics, optimization, and physics. Based on these experiences, we extract common techniques for effective human-AI collaboration in theoretical research, such as iterative refinement, problem decomposition, and cross-disciplinary knowledge transfer. While the majority of our results stem from this interactive, conversational methodology, we also highlight specific instances that push beyond standard chat interfaces. These include deploying the model as a rigorous adversarial reviewer to detect subtle flaws in existing proofs, and embedding it within a "neuro-symbolic" loop that autonomously writes and executes code to verify complex derivations. Together, these examples highlight the potential of AI not just as a tool for automation, but as a versatile, genuine partner in the creative process of scientific discovery.

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