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Improved motif-scaffolding with SE(3) flow matching

Improved motif-scaffolding with SE(3) flow matching

8 January 2024
Jason Yim
Andrew Campbell
Emile Mathieu
Andrew Y. K. Foong
Michael Gastegger
José Jiménez-Luna
Sarah Lewis
Victor Garcia Satorras
Bastiaan S. Veeling
Frank Noé
Regina Barzilay
Tommi Jaakkola
ArXivPDFHTML

Papers citing "Improved motif-scaffolding with SE(3) flow matching"

21 / 21 papers shown
Title
An All-Atom Generative Model for Designing Protein Complexes
An All-Atom Generative Model for Designing Protein Complexes
Ruizhe Chen
Dongyu Xue
Xiangxin Zhou
Zaixiang Zheng
Xiangxiang Zeng
Quanquan Gu
19
0
0
17 Apr 2025
ProtFlow: Fast Protein Sequence Design via Flow Matching on Compressed Protein Language Model Embeddings
ProtFlow: Fast Protein Sequence Design via Flow Matching on Compressed Protein Language Model Embeddings
Zitai Kong
Yiheng Zhu
Yinlong Xu
Hanjing Zhou
Mingzhe Yin
Jialu Wu
Hongxia Xu
Chang-Yu Hsieh
Tingjun Hou
J. Wu
24
0
0
15 Apr 2025
Elucidating the Design Space of Multimodal Protein Language Models
Elucidating the Design Space of Multimodal Protein Language Models
Cheng-Yen Hsieh
X. Wang
Daiheng Zhang
Dongyu Xue
Fei Ye
Shujian Huang
Zaixiang Zheng
Quanquan Gu
29
1
0
15 Apr 2025
PolyConf: Unlocking Polymer Conformation Generation through Hierarchical Generative Models
PolyConf: Unlocking Polymer Conformation Generation through Hierarchical Generative Models
Fanmeng Wang
Wentao Guo
Qi Ou
Hongshuai Wang
Haitao Lin
Hongteng Xu
Zhifeng Gao
AI4CE
27
1
0
11 Apr 2025
Integrating Protein Dynamics into Structure-Based Drug Design via Full-Atom Stochastic Flows
Xiangxin Zhou
Yi Xiao
Haowei Lin
Xinheng He
Jiaqi Guan
Yang Wang
Qiang Liu
F. I. S. Kevin Zhou
Liang Wang
Jianzhu Ma
AI4CE
50
0
0
06 Mar 2025
Proteina: Scaling Flow-based Protein Structure Generative Models
Tomas Geffner
Kieran Didi
Zuobai Zhang
Danny Reidenbach
Zhonglin Cao
...
Mario Geiger
Christian Dallago
E. Küçükbenli
Arash Vahdat
Karsten Kreis
DiffM
AI4CE
41
4
0
02 Mar 2025
MotifBench: A standardized protein design benchmark for motif-scaffolding problems
MotifBench: A standardized protein design benchmark for motif-scaffolding problems
Zhuoqi Zheng
Bo Zhang
Kieran Didi
Kevin K. Yang
Jason Yim
Joseph L. Watson
Hai-Feng Chen
Brian L. Trippe
43
1
0
20 Feb 2025
Learning conformational ensembles of proteins based on backbone geometry
Nicolas Wolf
Leif Seute
Vsevolod Viliuga
Simon Wagner
Jan Stühmer
Frauke Gräter
AI4CE
45
0
0
19 Feb 2025
ProteinWeaver: A Divide-and-Assembly Approach for Protein Backbone
  Design
ProteinWeaver: A Divide-and-Assembly Approach for Protein Backbone Design
Yiming Ma
Fei Ye
Yi Zhou
Zaixiang Zheng
Dongyu Xue
Quanquan Gu
56
0
0
08 Nov 2024
Training Free Guided Flow Matching with Optimal Control
Training Free Guided Flow Matching with Optimal Control
Luran Wang
Chaoran Cheng
Yizhen Liao
Yanru Qu
Ge Liu
31
1
0
23 Oct 2024
Efficient Antibody Structure Refinement Using Energy-Guided SE(3) Flow
  Matching
Efficient Antibody Structure Refinement Using Energy-Guided SE(3) Flow Matching
Jiying Zhang
Zijing Liu
Shengyuan Bai
He Cao
Yu Li
Lei Zhang
DiffM
22
1
0
22 Oct 2024
DPLM-2: A Multimodal Diffusion Protein Language Model
DPLM-2: A Multimodal Diffusion Protein Language Model
X. Wang
Zaixiang Zheng
Fei Ye
Dongyu Xue
Shujian Huang
Quanquan Gu
20
13
0
17 Oct 2024
MOFFlow: Flow Matching for Structure Prediction of Metal-Organic Frameworks
MOFFlow: Flow Matching for Structure Prediction of Metal-Organic Frameworks
N. Kim
Seongsu Kim
Minsu Kim
Jinkyoo Park
Sungsoo Ahn
AI4CE
28
0
0
07 Oct 2024
ProteinBench: A Holistic Evaluation of Protein Foundation Models
ProteinBench: A Holistic Evaluation of Protein Foundation Models
Fei Ye
Zaixiang Zheng
Dongyu Xue
Yuning Shen
Lihao Wang
Yiming Ma
Yan Wang
X. Wang
Xiangxin Zhou
Quanquan Gu
ELM
25
6
0
10 Sep 2024
Secondary Structure-Guided Novel Protein Sequence Generation with Latent
  Graph Diffusion
Secondary Structure-Guided Novel Protein Sequence Generation with Latent Graph Diffusion
Yutong Hu
Y. Tan
Andi Han
Lirong Zheng
Liang Hong
Bingxin Zhou
DiffM
15
1
0
10 Jul 2024
Full-Atom Peptide Design based on Multi-modal Flow Matching
Full-Atom Peptide Design based on Multi-modal Flow Matching
Jiahan Li
Chaoran Cheng
Zuofan Wu
Ruihan Guo
Shitong Luo
Zhizhou Ren
Jian-wei Peng
Jianzhu Ma
32
14
0
02 Jun 2024
Sequence-Augmented SE(3)-Flow Matching For Conditional Protein Backbone
  Generation
Sequence-Augmented SE(3)-Flow Matching For Conditional Protein Backbone Generation
Guillaume Huguet
James Vuckovic
Kilian Fatras
Eric Thibodeau-Laufer
Pablo Lemos
...
Jarrid Rector-Brooks
Tara Akhound-Sadegh
Michael M. Bronstein
Alexander Tong
A. Bose
32
26
0
30 May 2024
Trivialized Momentum Facilitates Diffusion Generative Modeling on Lie Groups
Trivialized Momentum Facilitates Diffusion Generative Modeling on Lie Groups
Yuchen Zhu
Tianrong Chen
Lingkai Kong
Evangelos A. Theodorou
Molei Tao
DiffM
35
3
0
25 May 2024
Out of Many, One: Designing and Scaffolding Proteins at the Scale of the
  Structural Universe with Genie 2
Out of Many, One: Designing and Scaffolding Proteins at the Scale of the Structural Universe with Genie 2
Yeqing Lin
Minji Lee
Zhao Zhang
Mohammed AlQuraishi
DiffM
27
17
0
24 May 2024
Extended Flow Matching: a Method of Conditional Generation with
  Generalized Continuity Equation
Extended Flow Matching: a Method of Conditional Generation with Generalized Continuity Equation
Noboru Isobe
Masanori Koyama
Jinzhe Zhang
Kohei Hayashi
Kenji Fukumizu
25
10
0
29 Feb 2024
Palette: Image-to-Image Diffusion Models
Palette: Image-to-Image Diffusion Models
Chitwan Saharia
William Chan
Huiwen Chang
Chris A. Lee
Jonathan Ho
Tim Salimans
David J. Fleet
Mohammad Norouzi
DiffM
VLM
325
1,570
0
10 Nov 2021
1